Structure of PDB 1u8o Chain B

Receptor sequence

>1u8oB (length=227) Species: 9606 (Homo sapiens) [Search protein sequence]

RITLKESGPPLVKPTQTLTLTCSFSGFSLSDFGVGVGWIRQPPGKALEWL
AIIYSDDDKRYSPSLNTRLTITKDTSKNQVVLVMTRVSPVDTATYFCAHR
RGPTTLFGVPIARGPVNAMDVWGQGITVTISSTSTKGPSVFPLAPGAAAA
LGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSS
SLQTYTCNVNHKPSNTKVDKRVEPKSC

3D structure

PDB

1u8o Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications

Chain

Resolution

3.02 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	Y52 D54 R58 R95 P98 R100H V100K	Y54 D56 R60 R100 P103 R113 V116

External links

PDB	RCSB:1u8o, PDBe:1u8o, PDBj:1u8o
PDBsum	1u8o
PubMed	19740978

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