Structure of PDB 1u8k Chain B

Receptor sequence

>1u8kB (length=228) Species: 9606 (Homo sapiens) [Search protein sequence]

RITLKESGPPLVKPTQTLTLTCSFSGFSLSDFGVGVGWIRQPPGKALEWL
AIIYSDDDKRYSPSLNTRLTITKDTSKNQVVLVMTRVSPVDTATYFCAHR
RGPTTLFGVPIARGPVNAMDVWGQGITVTISSTSTKGPSVFPLAPCSTAA
LGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSS
SLGTQTYTCNVNHKPSNTKVDKRVEPKS

3D structure

PDB

1u8k Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptides and Peptide Mimetics

Chain

Resolution

2.24 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	G33 Y52 D56 R95 P98 R100H V100K	G33 Y54 D58 R100 P103 R113 V116

External links

PDB	RCSB:1u8k, PDBe:1u8k, PDBj:1u8k
PDBsum	1u8k
PubMed

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