Structure of PDB 1tyl Chain B

Receptor sequence
>1tylB (length=30) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB1tyl The structure of a complex of hexameric insulin and 4'-hydroxyacetanilide.
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B Q4 H5 L6 C7 L15 V18 C19 R22 G23 F24 F25 P28 Q4 H5 L6 C7 L15 V18 C19 R22 G23 F24 F25 P28
BS02 peptide B G8 V12 E13 Y16 G23 F24 F25 Y26 G8 V12 E13 Y16 G23 F24 F25 Y26
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:1tyl, PDBe:1tyl, PDBj:1tyl
PDBsum1tyl
PubMed8090735
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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