Structure of PDB 1tr7 Chain B

Receptor sequence
>1tr7B (length=158) Species: 562 (Escherichia coli) [Search protein sequence]
FACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPE
TITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTD
KPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYA
NNDVVVPT
3D structure
PDB1tr7 Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DEG B F1 I13 N46 D47 D54 N135 D140 F1 I13 N46 D47 D54 N135 D140 MOAD: Kd=0.15uM
PDBbind-CN: -logKd/Ki=6.82,Kd=0.15uM
Gene Ontology
Cellular Component
GO:0009289 pilus

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Biological Process
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Cellular Component
External links
PDB RCSB:1tr7, PDBe:1tr7, PDBj:1tr7
PDBsum1tr7
PubMed15659162
UniProtP08191|FIMH_ECOLI Type 1 fimbrin D-mannose specific adhesin (Gene Name=fimH)

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