Structure of PDB 1tfc Chain B

Receptor sequence
>1tfcB (length=225) Species: 9606 (Homo sapiens) [Search protein sequence]
PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGW
AKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIM
DEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHI
EDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAV
QHFYNIKLEGKVPMHKLFLEMLEAK
3D structure
PDB1tfc Structural Basis for the Deactivation of the Estrogen-related Receptor {gamma} by Diethylstilbestrol or 4-Hydroxytamoxifen and Determinants of Selectivity.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I280 K284 L294 M298 K448 L449 E452 M453 I48 K52 L62 M66 K216 L217 E220 M221
External links
PDB RCSB:1tfc, PDBe:1tfc, PDBj:1tfc
PDBsum1tfc
PubMed15161930
UniProtP62508|ERR3_HUMAN Estrogen-related receptor gamma (Gene Name=ESRRG)

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