Structure of PDB 1t5c Chain B

Receptor sequence
>1t5cB (length=310) Species: 9606 (Homo sapiens) [Search protein sequence]
GAVAVCVRVRPLNAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTKNVY
EEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGSEDHLGVIPRAIHDI
FQKIKKFPDREFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVY
VADLTEEVVYTSEMALKWITKGEKSRHYGETKMNQRSSRSHTIFRMILES
REKSVKVSHLNLVDLAGSERAALKEGCNINRSLFILGQVIKKLSDGQVGG
FINYRDSKLTRILQNSLGGNAKTRIICTITPVSFDETLTALQFASTAKYM
KNTPYVNEVS
3D structure
PDB1t5c Crystal structure of the motor domain of the human kinetochore protein CENP-E.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B R12 P15 T88 A89 S90 G91 K92 T93 Y94 R8 P11 T75 A76 S77 G78 K79 T80 Y81
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:1t5c, PDBe:1t5c, PDBj:1t5c
PDBsum1t5c
PubMed15236970
UniProtQ02224|CENPE_HUMAN Centromere-associated protein E (Gene Name=CENPE)

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