Structure of PDB 1t47 Chain B

Receptor sequence
>1t47B (length=362) Species: 33903 (Streptomyces avermitilis) [Search protein sequence]
DPFPVKGMDAVVFAVGNAKQAAHYYSTAFGMQLVAYSGPENGSRETASYV
LTNGSARFVLTSVIKPATPWGHFLADHVAEHGDGVVDLAIEVPDARAAHA
YAIEHGARSVAEPYELKDEHGTVVLAAIATYGKTRHTLVDRTGYDGPYLP
GYVAAAPIVEPPAHRTFQAIDHCVGNVELGRMNEWVGFYNKVMGFTNMKE
FVGDDIATEYSALMSKVVADGTLKVKFPINEPALAKKKSQIDEYLEFYGG
AGVQHIALNTGDIVETVRTMRAAGVQFLDTPDSYYDTLGEWVGDTRVPVD
TLRELKILADRDEDGYLLQIFTKPVQDRPTVFFEIIERHGSMGFGKGNFK
ALFEAIEREQEK
3D structure
PDB1t47 Structure of the Ferrous Form of (4-Hydroxyphenyl)pyruvate Dioxygenase from Streptomyces avermitilis in Complex with the Therapeutic Herbicide, NTBC
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.13.11.27: 4-hydroxyphenylpyruvate dioxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE2 B H187 H270 E349 H172 H255 E334
BS02 NTD B H187 S230 P243 H270 F336 F347 F359 G360 N363 F364 L367 H172 S215 P228 H255 F321 F332 F344 G345 N348 F349 L352
Gene Ontology
Molecular Function
GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity
GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0006559 L-phenylalanine catabolic process
GO:0006572 tyrosine catabolic process
GO:0009072 aromatic amino acid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1t47, PDBe:1t47, PDBj:1t47
PDBsum1t47
PubMed15157070
UniProtQ53586|HPPD_STRAW 4-hydroxyphenylpyruvate dioxygenase (Gene Name=hpd)

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