Structure of PDB 1t34 Chain B

Receptor sequence
>1t34B (length=421) Species: 10116 (Rattus norvegicus) [Search protein sequence]
SDLTVAVVLPLTNTSYPWSWARVGPAVELALARVKARPDLLPGWTVRMVL
GSSENAAGVCSDTAAPLAAVDLKWEHSPAVFLGPGCVYSAAPVGRFTAHW
RVPLLTAGAPALGIGVKDEYALTTRTGPSHVKLGDFVTALHRRLGWEHQA
LVLYADRLGDDRPCFFIVEGLYMRVRERLNITVNHQEFVEGDPDHYPKLL
RAVRRKGRVIYICSSPDAFRNLMLLALNAGLTGEDYVFFHLDVFGQSLKS
AQQKPWERGDGQDRSARQAFQAAKIITYKEPDNPEYLEFLKQLKLLADKK
FNFTVEDGLKNIIPASFHDGLLLYVQAVTETLAQGGTVTDGENITQRMWN
RSFQGVTGYLKIDRNGDRDTDFSLWDMDPETGAFRVVLNYNGTSQELMAV
SEHKLYWPLGYPPPDVPKCGF
3D structure
PDB1t34 Crystal structure of hormone-bound atrial natriuretic peptide receptor extracellular domain: rotation mechanism for transmembrane signal transduction
ChainB
Resolution2.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.6.1.2: guanylate cyclase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B D62 Y88 A91 R95 H185 Q186 E187 K198 D62 Y88 A91 R95 H185 Q186 E187 K198
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:1t34, PDBe:1t34, PDBj:1t34
PDBsum1t34
PubMed15117952
UniProtP18910|ANPRA_RAT Atrial natriuretic peptide receptor 1 (Gene Name=Npr1)

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