Structure of PDB 1t2k Chain B

Receptor sequence
>1t2kB (length=108) Species: 9606 (Homo sapiens) [Search protein sequence]
PKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGI
FQAWAEATGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDP
HKIYEFVN
3D structure
PDB1t2k Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer.
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B K5 W38 H40 G41 K77 R81 N85 K105 K2 W35 H37 G38 K74 R78 N82 K102
BS02 dna B R7 I8 H40 L42 R43 W57 R78 N79 R86 K87 K98 R4 I5 H37 L39 R40 W54 R75 N76 R83 K84 K95
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1t2k, PDBe:1t2k, PDBj:1t2k
PDBsum1t2k
PubMed15510218
UniProtQ14653|IRF3_HUMAN Interferon regulatory factor 3 (Gene Name=IRF3)

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