Structure of PDB 1t1p Chain B
Receptor sequence
>1t1pB (length=30) Species:
9606
(Homo sapiens) [
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FVNQHLCGSDLTEALYLVCGERGFFYTKPT
3D structure
PDB
1t1p
How Insulin Binds: the B-Chain alpha-Helix Contacts the L1 beta-Helix of the Insulin Receptor.
Chain
B
Resolution
N/A
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
B
F1 N3 Q4 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 Y26 T27
F1 N3 Q4 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 Y26 T27
Gene Ontology
Molecular Function
GO:0005179
hormone activity
Cellular Component
GO:0005576
extracellular region
View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB
RCSB:1t1p
,
PDBe:1t1p
,
PDBj:1t1p
PDBsum
1t1p
PubMed
15276842
UniProt
P01308
|INS_HUMAN Insulin (Gene Name=INS)
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