Structure of PDB 1sy7 Chain B

Receptor sequence

>1sy7B (length=698) Species: 5141 (Neurospora crassa) [Search protein sequence]

ARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPE
RVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRG
SADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPE
PHNEVPQAQSAHNNFWDFQFNHTEATHMFTWAMSDRAIPRSLRMMQGFGV
NTYTLINAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWE
AIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDLVPVRYIGEME
LNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLG
VNFQELPINRPVCPVMNFNRDGAMRHTISRGTVNYYPNRFDACPPASLKE
GGYLEYAQKVAGIKARARSAKFKEHFSQAQLFYNSMSPIEKQHMINAFGF
ELDHCEDPVVYGRMVQRLADIDLGLAQTIAEMVGGEAPTTTNHPNHGRKT
INLSQTEFPPATPTIKSRRVAIIIADGYDNVAYDAAYAAISANQAIPLVI
GPRRSKVTAANGSTVQPHHHLEGFRSTMVDAIFIPGGAKAAETLSKNGRA
LHWIREAFGHLKAIGATGEAVDLVAKAIALPQVTVSSEAEVHESYGVVTL
KKVKPESFTDAVKIAKGAAGFLGEFFYAIAQHRNWDRELDGLHSMIAY

3D structure

PDB

1sy7 Unusual Cys-Tyr covalent bond in a large catalase

Chain

Resolution

1.75 Å

3D
structure

Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Catalytic site (original residue number in PDB)	H92 N165 C356
Catalytic site (residue number reindexed from 1)	H54 N127 C318
Enzyme Commision number	1.11.1.6: catalase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HDD	B	R89 V91 H92 R129 V163 G164 N165 F170 F178 V238 N239 F355 L371 G374 R375 S378 Y379 T382	R51 V53 H54 R91 V125 G126 N127 F132 F140 V200 N201 F317 L333 G336 R337 S340 Y341 T344
BS02	HEM	B	R89 V91 H92 R129 V163 G164 N165 F170 A175 F178 V238 N239 F355 L371 R375 S378 Y379 T382 Q383 R386	R51 V53 H54 R91 V125 G126 N127 F132 A137 F140 V200 N201 F317 L333 R337 S340 Y341 T344 Q345 R348

Gene Ontology

	Molecular Function
GO:0004096	catalase activity
GO:0004601	peroxidase activity
GO:0020037	heme binding
GO:0046872	metal ion binding

	Biological Process
GO:0006979	response to oxidative stress
GO:0042744	hydrogen peroxide catabolic process
GO:0048315	conidium formation
GO:0098869	cellular oxidant detoxification

	Cellular Component
GO:0005576	extracellular region
GO:0005619	ascospore wall
GO:0005829	cytosol

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:1sy7, PDBe:1sy7, PDBj:1sy7
PDBsum	1sy7
PubMed	15342250
UniProt	Q9C168\|CAT1_NEUCR Catalase-1 (Gene Name=cat-1)

[Back to BioLiP]