Structure of PDB 1spg Chain B

Receptor sequence

>1spgB (length=147) Species: 59837 (Leiostomus xanthurus)

VDWTDAERAAIKALWGKIDVGEIGPQALSRLLIVYPWTQRHFKGFGNIST
NAAILGNAKVAEHGKTVMGGLDRAVQNMDNIKNVYKQLSIKHSEKIHVDP
DNFRLLGEIITMCVGAKFGPSAFTPEIHEAWQKFLAVVVSALGRQYH

3D structure

• PDB: 1spg Structural basis for the root effect in haemoglobin.
• Chain: B
• Resolution: 1.95 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	B	H41 F42 H63 L88 H92 I96 V98 N102 L142	H41 F42 H63 L88 H92 I96 V98 N102 L142

Gene Ontology

Molecular Function

• GO:0004601 peroxidase activity
• GO:0005344 oxygen carrier activity
• GO:0019825 oxygen binding
• GO:0020037 heme binding
• GO:0031720 haptoglobin binding
• GO:0043177 organic acid binding
• GO:0046872 metal ion binding

Biological Process

• GO:0015671 oxygen transport
• GO:0042744 hydrogen peroxide catabolic process
• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0005833 hemoglobin complex
• GO:0031838 haptoglobin-hemoglobin complex
• GO:0072562 blood microparticle

External links

• PDB: RCSB:1spg, PDBe:1spg, PDBj:1spg
• PDBsum: 1spg
• PubMed: 8605630
• UniProt: P56251|HBB_LEIXA Hemoglobin subunit beta (Gene Name=hbb)