Structure of PDB 1sk6 Chain B

Receptor sequence
>1sk6B (length=454) Species: 1392 (Bacillus anthracis) [Search protein sequence]
DVLKGEKALKASGLVPEHADAFKKIARELNTYILFRPVNKLATNLIKSGV
ATKGLNVHGKSSDWGPVAGYIPFDQDLSKKHGQQLAVEKGNLENKKSITE
HEGEIGKIPLKLDHLRIEELKENGIILKGKKEIDNGKKYYLLESNNQVYE
FRISDENNEVQYKTKEGKITVLGEKFNWRNIEVMAKNVEGVLKPLTADYD
LFALAPSLTEIKKQIPQKEWDKVVNTPNEKQKGVTNLLIKYGIERKPDST
KGTLSNWQKQMLDRLNEAVKYTGYTGGDVVNHGTEQDNEEFPEKDNEIFI
INPEGEFILTKNWEMTGRFIEKNITGKDYLYYFNRSYNKIAPGNKAYIEW
TDPITKAKINTIPSDYYNSANHIFSQEKKRKISIFRGIQAYNEIENVLKS
KQIAPEYKNYFQYLKERITNQVQLLLTHQKLLYKQLNFTENETDNFEVFQ
KIID
3D structure
PDB1sk6 Structural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and pyrophosphate.
ChainB
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.6.1.1: adenylate cyclase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YB B K346 D491 D493 K53 D198 D200
BS02 YB B D491 D493 H577 D198 D200 H282
BS03 CMP B H351 G547 T548 G578 N583 H58 G252 T253 G283 N288
BS04 POP B K346 K353 S354 K372 A490 K53 K60 S61 K79 A197
Gene Ontology
Molecular Function
GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:1sk6, PDBe:1sk6, PDBj:1sk6
PDBsum1sk6
PubMed15131111
UniProtP40136|CYAA_BACAN Calmodulin-sensitive adenylate cyclase (Gene Name=cya)

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