Structure of PDB 1s5y Chain B

Receptor sequence

>1s5yB (length=136) Species: 40690 (Trematomus bernacchii)

VEWTDKERSIISDIFSHMDYDDIGPKALSRCLIVYPWTQRHFSGAIIGNA
NVAAHGIKVLHGLDRGVKNMDNIAATYADLSTLHSEKLHVDPDNFKLLSD
CITIVLAAKMGHAFTAETQGAFQKFLAVVVSALGKQ

3D structure

• PDB: 1s5y The oxidation process of Antarctic fish hemoglobins
• Chain: B
• Resolution: 2.5 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	B	H41 F42 H63 K66 V67 L88 H92 L96 V98 N102 F103	H41 F42 H55 K58 V59 L80 H84 L88 V90 N94 F95

Gene Ontology

Molecular Function

• GO:0004601 peroxidase activity
• GO:0005344 oxygen carrier activity
• GO:0019825 oxygen binding
• GO:0020037 heme binding
• GO:0031720 haptoglobin binding
• GO:0043177 organic acid binding
• GO:0046872 metal ion binding

Biological Process

• GO:0015671 oxygen transport
• GO:0042744 hydrogen peroxide catabolic process
• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0005833 hemoglobin complex
• GO:0031838 haptoglobin-hemoglobin complex
• GO:0072562 blood microparticle

External links

• PDB: RCSB:1s5y, PDBe:1s5y, PDBj:1s5y
• PDBsum: 1s5y
• PubMed: 15096204
• UniProt: P80044|HBB_TREBE Hemoglobin subunit beta (Gene Name=hbb)