Structure of PDB 1s5r Chain B

Receptor sequence
>1s5rB (length=89) Species: 10090 (Mus musculus) [Search protein sequence]
SLQNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKE
AGGNYTPALTEQEVYAQVARLFKNQEDLLSEFGQFLPDA
3D structure
PDB1s5r HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations.
ChainB
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B E303 A307 N312 L329 L332 Y335 Q336 Q339 F376 Q378 F379 P381 D382 E9 A13 N18 L35 L38 Y41 Q42 Q45 F82 Q84 F85 P87 D88
Gene Ontology
Molecular Function
GO:0003714 transcription corepressor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1s5r, PDBe:1s5r, PDBj:1s5r
PDBsum1s5r
PubMed15235594
UniProtQ60520|SIN3A_MOUSE Paired amphipathic helix protein Sin3a (Gene Name=Sin3a)

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