Structure of PDB 1s5q Chain B

Receptor sequence
>1s5qB (length=89) Species: 10090 (Mus musculus) [Search protein sequence]
SLQNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKE
AGGNYTPALTEQEVYAQVARLFKNQEDLLSEFGQFLPDA
3D structure
PDB1s5q HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations.
ChainB
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B E303 A307 I308 L332 Y335 Q336 Q339 F376 F379 E9 A13 I14 L38 Y41 Q42 Q45 F82 F85
Gene Ontology
Molecular Function
GO:0003714 transcription corepressor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1s5q, PDBe:1s5q, PDBj:1s5q
PDBsum1s5q
PubMed15235594
UniProtQ60520|SIN3A_MOUSE Paired amphipathic helix protein Sin3a (Gene Name=Sin3a)

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