Structure of PDB 1s5k Chain B

Receptor sequence
>1s5kB (length=134) [Search protein sequence]
DIRQMNKTHLEHWRGLRKQLADGEEILQADHLASFIAMADGVAIGFADAS
IRHDYVNGCDSSPVVFLEGIFVLPSFRQRGVAKQLIAAVQRWGTNKGCRE
MASDTSPENTISQKVHQALGFEETERVIFYRKRC
3D structure
PDB1s5k A bacterial acetyltransferase capable of regioselective N-acetylation of antibiotics and histones
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.82: aminoglycoside 6'-N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA B I81 F82 V83 R88 Q89 G91 A93 K94 I122 V126 A129 I70 F71 V72 R77 Q78 G80 A82 K83 I111 V115 A118
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0042803 protein homodimerization activity
GO:0047663 aminoglycoside 6'-N-acetyltransferase activity
Biological Process
GO:0006084 acetyl-CoA metabolic process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:1s5k, PDBe:1s5k, PDBj:1s5k
PDBsum1s5k
PubMed15123251
UniProtQ9R381|AAC6_SALEN Aminoglycoside N(6')-acetyltransferase type 1

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