Structure of PDB 1s18 Chain B

Receptor sequence
>1s18B (length=315) Species: 9606 (Homo sapiens) [Search protein sequence]
YNDTYPLSPPQRTPAGIRYRIAVIADLDTESRAQEENTWFSYLKKGYLTL
SDSGDKVAVEWDKDHGVLESHLAEKGRGMELSDLIVFNGKLYSVDDRTGV
VYQIEGSKAVPWVILSDGDGTVEKGFKAEWLAVKDERLYVGGLGKEWTTT
TGDVVNENPEWVKVVGYKGSVDHENWVSNYNALRAAAGIQPPGYLIHESA
CWSDTLQRWFFLPRRASQERYSEKDDERKGANLLLSASPDFGDIAVSHVG
AVVPTHGFSSFKFIPNTDDQIIVALKSEEDSGRVASYIMAFTLDGRFLLP
ETKIGSVKYEGIEFI
3D structure
PDB1s18 Structure and protein design of a human platelet function inhibitor.
ChainB
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.6: nucleoside diphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B S98 D99 E145 E214 S275 E326 S82 D83 E129 E198 S259 E310
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0017110 nucleoside diphosphate phosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:1s18, PDBe:1s18, PDBj:1s18
PDBsum1s18
PubMed15006348
UniProtQ8WVQ1|CANT1_HUMAN Soluble calcium-activated nucleotidase 1 (Gene Name=CANT1)

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