Structure of PDB 1ryh Chain B

Receptor sequence
>1ryhB (length=167) Species: 9606 (Homo sapiens) [Search protein sequence]
GSMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDG
KPVNLGLWDTIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILV
GTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQR
GLKTVFDEAIRAVLCPP
3D structure
PDB1ryh Alternative Splicing of Rac1 Generates Rac1b, a Self-activating GTPase
ChainB
Resolution1.75 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP B A13 G15 K16 T17 C18 F28 K135 D137 L138 S177 A178 L179 A15 G17 K18 T19 C20 F30 K103 D105 L106 S145 A146 L147
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007264 small GTPase-mediated signal transduction

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1ryh, PDBe:1ryh, PDBj:1ryh
PDBsum1ryh
PubMed14625275
UniProtP63000|RAC1_HUMAN Ras-related C3 botulinum toxin substrate 1 (Gene Name=RAC1)

[Back to BioLiP]