Structure of PDB 1ruo Chain B

Receptor sequence
>1ruoB (length=201) Species: 562 (Escherichia coli) [Search protein sequence]
PTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKE
MILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKKFRQLIQV
NPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMT
HPDGMQIKITRQEIGQIVGCSRFTVGRILKMLEDQNLISAHGKTIVVYGT
R
3D structure
PDB1ruo Aromatic hydrogen bond in sequence-specific protein DNA recognition.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B D138 V139 S179 F181 T182 H199 G200 D130 V131 S171 F173 T174 H191 G192
BS02 dna B T168 R169 Q170 R180 G184 R185 T160 R161 Q162 R172 G176 R177
BS03 CMP B L124 S128 L116 S120
BS04 CMP B V49 L61 S62 G71 E72 L73 R82 S83 A84 V41 L53 S54 G63 E64 L65 R74 S75 A76
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003680 minor groove of adenine-thymine-rich DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005515 protein binding
GO:0008301 DNA binding, bending
GO:0030552 cAMP binding
GO:0042802 identical protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription
GO:0045013 carbon catabolite repression of transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol
GO:0032993 protein-DNA complex

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Cellular Component
External links
PDB RCSB:1ruo, PDBe:1ruo, PDBj:1ruo
PDBsum1ruo
PubMed8836098
UniProtP0ACJ8|CRP_ECOLI DNA-binding transcriptional dual regulator CRP (Gene Name=crp)

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