Structure of PDB 1rje Chain B

Receptor sequence
>1rjeB (length=329) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
ERIIQQTDYDALSCKLAAISVGYLPSSGLQRLSVDLSKKYTEWHRSYLIT
LKKFSRRAFGKVDKAMRSSFPVMNYGTYLRTVGIDAAILEFLVANEKVQV
VNLGCGSDLRMLPLLQMFPHLAYVDIDYNESVELKNSILRESEILRISLG
LSKEDTAKSPFLIDQGRYKLAACDLNDITETTRLLDVCTKREIPTIVISE
CLLCYMHNNESQLLINTIMSKFSHGLWISYDPIGGSQPNDRFGAIMQSNL
KESRNLEMPTLMTYNSKEKYASRWSAAPNVIVNDMWEIFNAQIPESERKR
LRSLQFLDELEELKVMQTHYILMKAQWHH
3D structure
PDB1rje Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.233: [phosphatase 2A protein]-leucine-carboxy methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH B I5 T8 D9 G105 C106 D128 Y129 N177 E201 C202 L203 I4 T7 D8 G104 C105 D127 Y128 N176 E200 C201 L202
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0018423 protein C-terminal leucine carboxyl O-methyltransferase activity
Biological Process
GO:0010506 regulation of autophagy
GO:0032259 methylation
GO:0065003 protein-containing complex assembly
Cellular Component
GO:0005575 cellular_component

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Molecular Function
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Cellular Component
External links
PDB RCSB:1rje, PDBe:1rje, PDBj:1rje
PDBsum1rje
PubMed14660564
UniProtQ04081|LCMT1_YEAST Leucine carboxyl methyltransferase 1 (Gene Name=PPM1)

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