Structure of PDB 1rjd Chain B

Receptor sequence
>1rjdB (length=329) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
ERIIQQTDYDALSCKLAAISVGYLPSSGLQRLSVDLSKKYTEWHRSYLIT
LKKFSRRAFGKVDKAMRSSFPVMNYGTYLRTVGIDAAILEFLVANEKVQV
VNLGCGSDLRMLPLLQMFPHLAYVDIDYNESVELKNSILRESEILRISLG
LSKEDTAKSPFLIDQGRYKLAACDLNDITETTRLLDVCTKREIPTIVISE
CLLCYMHNNESQLLINTIMSKFSHGLWISYDPIGGSQPNDRFGAIMQSNL
KESRNLEMPTLMTYNSKEKYASRWSAAPNVIVNDMWEIFNAQIPESERKR
LRSLQFLDELEELKVMQTHYILMKAQWHH
3D structure
PDB1rjd Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity
ChainB
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.1.1.233: [phosphatase 2A protein]-leucine-carboxy methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM B I5 T8 D9 R81 G105 C106 D128 Y129 C174 D175 L176 N177 E201 C202 L203 I4 T7 D8 R80 G104 C105 D127 Y128 C173 D174 L175 N176 E200 C201 L202
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0018423 protein C-terminal leucine carboxyl O-methyltransferase activity
Biological Process
GO:0010506 regulation of autophagy
GO:0032259 methylation
GO:0065003 protein-containing complex assembly
Cellular Component
GO:0005575 cellular_component

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1rjd, PDBe:1rjd, PDBj:1rjd
PDBsum1rjd
PubMed14660564
UniProtQ04081|LCMT1_YEAST Leucine carboxyl methyltransferase 1 (Gene Name=PPM1)

[Back to BioLiP]