Structure of PDB 1re4 Chain B

Receptor sequence
>1re4B (length=306) Species: 9606 (Homo sapiens) [Search protein sequence]
DETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNI
PVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQ
NRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLT
RMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNAL
MDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEAGGGWW
YNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMK
IRPFFP
3D structure
PDB1re4 BbetaGlu397 and BbetaAsp398 but not BbetaAsp432 are required for "B:b" interactions.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B D381 D383 W385 D228 D230 W232
BS02 CA B D261 G263 D108 G110
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1re4, PDBe:1re4, PDBj:1re4
PDBsum1re4
PubMed14992584
UniProtP02675|FIBB_HUMAN Fibrinogen beta chain (Gene Name=FGB)

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