Structure of PDB 1r5v Chain B

Receptor sequence
>1r5vB (length=185) Species: 10090 (Mus musculus) [Search protein sequence]
APWFLEYSKSECHFYNGTQRVRLLVRYFYNLEENLRFDSDVGEFRAVTEL
GRPDAENWNSQPEFLEQKRAEVDTVCRHNYEIFDNFLVPRRVEPTVTVYP
TKTQPLEHHNLLVCSVSDFYPGNIEVRWFRNGKEEKTGIVSTGLVRNGDW
TFQTLVMLETVPQSGEVYTCQVEHPSLTDPVTVEW
3D structure
PDB1r5v Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation.
ChainB
Resolution2.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B E36 S40 D84 N87 W88 F94 E101 H108 N109 I112 F113 E6 S10 D54 N57 W58 F64 E71 H78 N79 I82 F83
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1r5v, PDBe:1r5v, PDBj:1r5v
PDBsum1r5v
PubMed14690592
UniProtP18468|HB2I_MOUSE H-2 class II histocompatibility antigen, I-A beta chain (Gene Name=H2-Eb1)

[Back to BioLiP]