Structure of PDB 1r0y Chain B

Receptor sequence
>1r0yB (length=267) Species: 10090 (Mus musculus) [Search protein sequence]
TTGIIMENVTAFWEEGFGELLEKVQSFSHLCLVGNPVLKNINLNIEKGEM
LAITGSTGSGKTSLLMLILGELEASEGIIKHSGRVSFCSQFSWIMPGTIK
ENIIFGVSYDEYRYKSVVKACQLQQDITKFAEQDNTVLGEGGVTLSGGQR
ARISLARAVYKDADLYLLDSPFGYLDVFTEEQVFESCVCKLMANKTRILV
TSKMEHLRKADKILILHQGSSYFYGTFSELQSLRPDFSSKLMGYDTFDQF
TEERRSSILTETLRRFS
3D structure
PDB1r0y Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator.
ChainB
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.1.6: channel-conductance-controlling ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B W401 Q413 F430 G461 S462 G463 K464 T465 S466 W13 Q25 F27 G58 S59 G60 K61 T62 S63
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:1r0y, PDBe:1r0y, PDBj:1r0y
PDBsum1r0y
PubMed14685259
UniProtP26361|CFTR_MOUSE Cystic fibrosis transmembrane conductance regulator (Gene Name=Cftr)

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