Structure of PDB 1qu4 Chain B

Receptor sequence
>1qu4B (length=356) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
DEGDPFFVADLGDIVRKHETWKKCLPRVTPFYAVKCNDDWRVLGTLAALG
TGFDCASNTEIQRVRGIGVPPEKIIYANPCKQISHIRYARDSGVDVMTFD
CVDELEKVAKTHPKAKMVLRISTLSVKFGAKVEDCRFILEQAKKLNIDVT
GVSFHVGSGSTDASTFAQAISDSRFVFDMGTELGFNMHILDIGGGFPGTR
DAPLKFEEIAGVINNALEKHFPPDLKLTIVAEPGRYYVASAFTLAVNVIA
KKVTPAQSFMYYVNDGVYGSFNCILYDHAVVRPLPQREPIPNEKLYPSSV
WGPTCDGLDQIVERYYLPEMQVGEWLLFEDMGAYTVVGTSSFNGFQSPTI
YYVVSG
3D structure
PDB1qu4 X-ray structure of ornithine decarboxylase from Trypanosoma brucei: the native structure and the structure in complex with alpha-difluoromethylornithine.
ChainB
Resolution2.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K69 H197 E274
Catalytic site (residue number reindexed from 1) K35 H155 E232
Enzyme Commision number 4.1.1.17: ornithine decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP B K69 H197 S200 G236 G237 E274 G276 R277 Y389 K35 H155 S158 G194 G195 E232 G234 R235 Y334
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004586 ornithine decarboxylase activity
GO:0016831 carboxy-lyase activity
Biological Process
GO:0006596 polyamine biosynthetic process
GO:0033387 putrescine biosynthetic process from ornithine
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1qu4, PDBe:1qu4, PDBj:1qu4
PDBsum1qu4
PubMed10563800
UniProtP07805|DCOR_TRYBB Ornithine decarboxylase

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