Structure of PDB 1qp9 Chain B

Receptor sequence
>1qp9B (length=74) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
KRNRIPLGCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAEEAE
KELLKDNELKKLRERVKSLEKTLS
3D structure
PDB1qp9 Structure of HAP1-PC7 bound to DNA: implications for DNA recognition and allosteric effects of DNA-binding on transcriptional activation.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R57 N58 R59 K71 W100 R2 N3 R4 K16 W45 PDBbind-CN: Kd=37.8nM
BS02 dna B K56 R57 R59 R68 K71 K73 K1 R2 R4 R13 K16 K18 PDBbind-CN: Kd=37.8nM
BS03 ZN B C64 C67 C74 C81 C9 C12 C19 C26
BS04 ZN B C64 C81 C93 C9 C26 C38
BS05 ZN B H80 H91 H25 H36
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1qp9, PDBe:1qp9, PDBj:1qp9
PDBsum1qp9
PubMed11024163
UniProtP0CS82|HAP1_YEASX Heme-responsive zinc finger transcription factor HAP1 (Gene Name=HAP1)

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