Structure of PDB 1qci Chain B

Receptor sequence
>1qciB (length=262) Species: 3527 (Phytolacca americana) [Search protein sequence]
VNTIIYNVGSTTISKYATFLNDLRNEAKDPSLKCYGIPMLPNTNTNPKYV
LVELQGSNKKTITLMLRRNNLYVMGYSDPFETNKCRYHIFNDISGTERQD
VETTLCPNANSRVSKNINFDSRYPTLESKAGVKSRSQVQLGIQILDSNIG
KISGVMSFTEKTEAEFLLVAIQMVSEAARFKYIENQVKTNFNRAFNPNPK
VLNLQETWGKISTAIHDAKNGVLPKPLELVDASGAKWIVLRVDEIKPDVA
LLNYVGGSCQTT
3D structure
PDB1qci X-ray crystallographic analysis of the structural basis for the interactions of pokeweed antiviral protein with its active site inhibitor and ribosomal RNA substrate analogs.
ChainB
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) V73 E176 R179
Catalytic site (residue number reindexed from 1) V73 E176 R179
Enzyme Commision number 3.2.2.22: rRNA N-glycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADE B Y72 V73 S121 I171 R179 Y72 V73 S121 I171 R179
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0030598 rRNA N-glycosylase activity
GO:0090729 toxin activity
Biological Process
GO:0017148 negative regulation of translation
GO:0035821 modulation of process of another organism
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:1qci, PDBe:1qci, PDBj:1qci
PDBsum1qci
PubMed10493577
UniProtP10297|RIP1_PHYAM Antiviral protein I (Gene Name=PAP1)

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