Structure of PDB 1q99 Chain B

Receptor sequence
>1q99B (length=364) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
GGYHPAFKGEPYKDARYILVRKLGWGHFSTVWLAKDMVNNTHVAMKIVRG
DKVYTEAAEDEIKLLQRVNDADNTKEDSMGANHILKLLDHFNHKGPNGVH
VVMVFEVLGENLLALIKKYEHRGIPLIYVKQISKQLLLGLDYMHRRCGII
HTDIKPENVLMEIVDSPENLIQIKIADLGNACWYDEHYTNSIQTREYRSP
EVLLGAPWGCGADIWSTACLIFELITGDFLFEPDEGHSYTKDDDHIAQII
ELLGELPSYLLRNGKYTRTFFNSRGLLRNISKLKFWPLEDVLTEKYKFSK
DEAKEISDFLSPMLQLDPRKRADAGGLVNHPWLKDTLGMEEIRVPDRELY
GSGSDIPGWFEEVR
3D structure
PDB1q99 Nucleotide-Induced Conformational Changes in the Saccharomyces cerevisiae SR Protein Kinase, Sky1p, Revealed by X-ray Crystallography
ChainB
Resolution2.11 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D294 K296 N299 D550 T567
Catalytic site (residue number reindexed from 1) D153 K155 N158 D177 T194
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP B W166 G167 H168 F169 V172 A185 K187 L249 D550 W25 G26 H27 F28 V31 A44 K46 L108 D177
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1q99, PDBe:1q99, PDBj:1q99
PDBsum1q99
PubMed12911299
UniProtQ03656|SKY1_YEAST Serine/threonine-protein kinase SKY1 (Gene Name=SKY1)

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