Structure of PDB 1q8y Chain B

Receptor sequence
>1q8yB (length=357) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
PAFKGEPYKDARYILVRKLGFSTVWLAKDMVNNTHVAMKIVRGDKVYTEA
AEDEIKLLQRVNDADNTKEDSMGANHILKLLDHFNHKGPNGVHVVMVFEV
LGENLLALIKKYEHRGIPLIYVKQISKQLLLGLDYMHRRCGIIHTDIKPE
NVLMEIVDSPENLIQIKIADLGNACWYDEHYTNSIQTREYRSPEVLLGAP
WGCGADIWSTACLIFELITGDFLFEPDEGHSYTKDDDHIAQIIELLGELP
SYLLRNGKYTRTFFNSRGLLRNISKLKFWPLEDVLTEKYKFSKDEAKEIS
DFLSPMLQLDPRKRADAGGLVNHPWLKDTLGMEEIRVPDRELYGSGSDIP
GWFEEVR
3D structure
PDB1q8y Nucleotide-Induced Conformational Changes in the Saccharomyces cerevisiae SR Protein Kinase, Sky1p, Revealed by X-Ray Crystallography
ChainB
Resolution2.05 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D294 K296 N299 D550 T567
Catalytic site (residue number reindexed from 1) D146 K148 N151 D170 T187
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADE B A185 E247 V248 L249 A37 E99 V100 L101
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:1q8y, PDBe:1q8y, PDBj:1q8y
PDBsum1q8y
PubMed12911299
UniProtQ03656|SKY1_YEAST Serine/threonine-protein kinase SKY1 (Gene Name=SKY1)

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