Structure of PDB 1q4j Chain B

Receptor sequence
>1q4jB (length=209) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
DNIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDAFVEFKNFKKEK
DTPFEQVPILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCG
VQDIHYKFNNTNLFKQNETTFLNEDLPKWSGYFEKLLKKNHTNNNNDKYY
FVGNNLTYADLAVFNLYDDIETKYPSSLKNFPLLKAHNEFISNLPNIKNY
ITNRKESVY
3D structure
PDB1q4j Native and inhibited structure of a Mu class-related glutathione S-transferase from Plasmodium falciparum
ChainB
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) Y9 K15 R20
Catalytic site (residue number reindexed from 1) Y7 K13 R18
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTX B F116 K117 T121 F114 K115 T119
BS02 GTX B Y9 F45 Q58 V59 Q71 S72 N111 Y7 F43 Q56 V57 Q69 S70 N109
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity

View graph for
Molecular Function
External links
PDB RCSB:1q4j, PDBe:1q4j, PDBj:1q4j
PDBsum1q4j
PubMed12972411
UniProtQ8ILQ7|GST_PLAF7 Glutathione S-transferase (Gene Name=GST)

[Back to BioLiP]