Structure of PDB 1q43 Chain B

Receptor sequence
>1q43B (length=188) Species: 10090 (Mus musculus) [Search protein sequence]
SRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGE
LNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYI
IREGTIGKKMYFIQHGVVSVLTEMKLSDGSYFGEICLLTRGRRTASVRAD
TYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRI
3D structure
PDB1q43 Structural basis for modulation and agonist specificity of HCN pacemaker channels
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP B V564 M572 F580 G581 E582 I583 C584 R591 T592 R632 V120 M124 F132 G133 E134 I135 C136 R143 T144 R184
External links
PDB RCSB:1q43, PDBe:1q43, PDBj:1q43
PDBsum1q43
PubMed12968185
UniProtO88703|HCN2_MOUSE Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Gene Name=Hcn2)

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