Structure of PDB 1q3e Chain B

Receptor sequence
>1q3eB (length=189) Species: 10090 (Mus musculus) [Search protein sequence]
DSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSIL
GELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGD
YIIREGTIGKKMYFIQHGVVSVLTEMKLSDGSYFGEICLLTRGRRTASVR
ADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDR
3D structure
PDB1q3e Structural basis for modulation and agonist specificity of HCN pacemaker channels
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PCG B V564 M572 F580 G581 E582 I583 C584 R591 T592 R632 V122 M126 F134 G135 E136 I137 C138 R145 T146 R186
External links
PDB RCSB:1q3e, PDBe:1q3e, PDBj:1q3e
PDBsum1q3e
PubMed12968185
UniProtO88703|HCN2_MOUSE Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Gene Name=Hcn2)

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