Structure of PDB 1px2 Chain B

Receptor sequence
>1px2B (length=294) Species: 10116 (Rattus norvegicus) [Search protein sequence]
ARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFS
VDMEVLRNGVKVVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPS
VNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSST
TYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKY
DVRVQKIGQNYKAYMRTWKTLEQIAMSDRYKLWVDTCSEIFGGLDICAVE
ALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQA
3D structure
PDB1px2 Tetramerization and ATP binding by a protein comprising the A, B, and C domains of rat synapsin I.
ChainB
Resolution2.23 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B E373 E386 E250 E263
BS02 ATP B K225 K269 H274 S275 G276 K279 E305 F307 I308 W335 T337 L375 E386 K113 K157 H162 S163 G164 K167 E193 F195 I196 W218 T220 L252 E263 MOAD: Kd=120nM
Gene Ontology
Biological Process
GO:0007269 neurotransmitter secretion
Cellular Component
GO:0008021 synaptic vesicle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1px2, PDBe:1px2, PDBj:1px2
PDBsum1px2
PubMed14688264
UniProtP09951|SYN1_RAT Synapsin-1 (Gene Name=Syn1)

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