Structure of PDB 1ppj Chain B

Receptor sequence
>1ppjB (length=424) Species: 9913 (Bos taurus) [Search protein sequence]
EVPPHPQDLEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYENSNNLGT
SHLLRLASSLTTKGASSFKITRGIEAVGGKLSVTSTRENMAYTVECLRDD
VDILMEFLLNVTTAPEFRRWEVAALQPQLRIDKAVALQNPQAHVIENLHA
AAYRNALANSLYCPDYRIGKVTPVELHDYVQNHFTSARMALIGLGVSHPV
LKQVAEQFLNIRGGLGLSGAKAKYHGGEIREQNGDSLVHAALVAESAAIG
SAEANAFSVLQHVLGAGPHVKRGSNATSSLYQAVAKGVHQPFDVSAFNAS
YSDSGLFGFYTISQAASAGDVIKAAYNQVKTIAQGNLSNPDVQAAKNKLK
AGYLMSVESSEGFLDEVGSQALAAGSYTPPSTVLQQIDAVADADVINAAK
KFVSGRKSMAASGNLGHTPFIDEL
3D structure
PDB1ppj Binding of the Respiratory Chain Inhibitor Antimycin to the Mitochondrial bc(1) Complex: A New Crystal Structure Reveals an Altered Intramolecular Hydrogen-bonding Pattern.
ChainB
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H67 R70 L71 L140 D147
Catalytic site (residue number reindexed from 1) H52 R55 L56 L125 D132
Enzyme Commision number 1.10.2.2: Transferred entry: 7.1.1.8.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 JZR B L75 S82 E136 A139 L140 L60 S67 E121 A124 L125
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:1ppj, PDBe:1ppj, PDBj:1ppj
PDBsum1ppj
PubMed16024040
UniProtP23004|QCR2_BOVIN Cytochrome b-c1 complex subunit 2, mitochondrial (Gene Name=UQCRC2)

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