Structure of PDB 1pn9 Chain B

Receptor sequence
>1pn9B (length=209) Species: 7165 (Anopheles gambiae) [Search protein sequence]
MDFYYLPGSAPCRAVQMTAAAVGVELNLKLTDLMKGEHMKPEFLKLNPQH
CIPTLVDNGFALWESRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLYFD
MGTLYQRFADYHYPQIFAKQPANPENEKKMKDAVGFLNTFLEGQEYAAGN
DLTIADLSLAATIATYEVAGFDFAPYPNVAAWFARCKANAPGYALNQAGA
DEFKAKFLS
3D structure
PDB1pn9 Structure of an insect delta-class glutathione S-transferase from a DDT-resistant strain of the malaria vector Anopheles gambiae.
ChainB
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S9
Catalytic site (residue number reindexed from 1) S9
Enzyme Commision number 2.5.1.18: glutathione transferase.
4.5.1.1: DDT-dehydrochlorinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTX B S9 L33 H50 C51 I52 E64 S65 Y113 S9 L33 H50 C51 I52 E64 S65 Y113
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity
GO:0016829 lyase activity
GO:0018833 DDT-dehydrochlorinase activity
Biological Process
GO:0006749 glutathione metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1pn9, PDBe:1pn9, PDBj:1pn9
PDBsum1pn9
PubMed14646079
UniProtQ93113|GST1D_ANOGA Glutathione S-transferase 1, isoform D (Gene Name=GstD1)

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