Structure of PDB 1pn3 Chain B

Receptor sequence
>1pn3B (length=384) Species: 31958 (Amycolatopsis orientalis) [Search protein sequence]
MRVLITGCGSRGDTEPLVALAARLRELGADARMCLPPDYVERCAEVGVPM
VPVGRAVRAGAREPGELPPGAAEVVTEVVAEWFDKVPAAIEGCDAVVTTG
LLPAAVAVRSMAEKLGIPYRYTVLSPDHLPSEQSQAERDMYNQGADRLFG
DAVNSHRASIGLPPVEHLYDYGYTDQPWLAADPVLSPLRPTDLGTVQTGA
WILPDERPLSAELEAFLAAGSTPVYVGFGSSSRPATADAAKMAIKAVRAS
GRRIVLSRGWADLVLPDDGADCFVVGEVNLQELFGRVAAAIHHDSAGTTL
LAMRAGIPQIVVRRVAYHADRVAELGVGVAVDGPVPTIDSLSAALDTALA
PEIRARATTVADTIRADGTTVAAQLLFDAVSLEK
3D structure
PDB1pn3 Structure of the Tdp-Epi-Vancosaminyltransferase Gtfa from the Chloroeremomycin Biosynthetic Pathway.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.311: dTDP-epi-vancosaminyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B S10 D13 G70 L101 L102 H128 Y141 A145 Y169 Y173 S10 D13 G70 L101 L102 H128 Y141 A145 Y169 Y173
BS02 BGC B H128 Q133 Y141 H128 Q133 Y141
Gene Ontology
Molecular Function
GO:0008194 UDP-glycosyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0017000 antibiotic biosynthetic process
GO:0030259 lipid glycosylation
GO:0033072 vancomycin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1pn3, PDBe:1pn3, PDBj:1pn3
PDBsum1pn3
PubMed12874381
UniProtP96558|GTFA_AMYOR dTDP-epi-vancosaminyltransferase (Gene Name=gtfA)

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