Structure of PDB 1pkk Chain B

Receptor sequence
>1pkkB (length=177) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence]
MILSDKDIIDYVTSKRIIIKPFNKDFVGPCSYDVTLGDEFIIYDDEVYDL
SKELNYKRIKIKNSILVCPLNYNLTEEKINYFKEKYNVDYVVEGGVLGTT
NEYIELPNDISAQYQGRSSLGRVFLTSHQTAGWIDAGFKGKITLEIVAFD
KPVILYKNQRIGQLIFSKLLSPADVGY
3D structure
PDB1pkk Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii
ChainB
Resolution1.77 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) S118 R122 A131 W133 E145
Catalytic site (residue number reindexed from 1) S118 R122 A131 W133 E145
Enzyme Commision number 3.5.4.30: dCTP deaminase (dUMP-forming).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DCP B H128 F138 T143 H128 F138 T143
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008829 dCTP deaminase activity
GO:0016787 hydrolase activity
GO:0033973 dCTP deaminase (dUMP-forming) activity
Biological Process
GO:0006226 dUMP biosynthetic process
GO:0006229 dUTP biosynthetic process
GO:0009117 nucleotide metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1pkk, PDBe:1pkk, PDBj:1pkk
PDBsum1pkk
PubMed12909016
UniProtQ57872|DCDB_METJA dCTP deaminase, dUMP-forming (Gene Name=dcd)

[Back to BioLiP]