Structure of PDB 1pkj Chain B

Receptor sequence
>1pkjB (length=175) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence]
MILSDKDIIDYVTSKRIIIKPFNKDFVGPCSYDVTLGDEFIIYDDEVYDL
SKELNYKRIKIKNSILVCPLNYNLTEEKINYFKEKYNVDYVVEGGVLGTT
NEYIELPNDISAQYQGRSSLGRVFLTSHQTAGWIDAGFKGKITLEIVAFD
KPVILYKNQRIGQLIFSKLLSPADV
3D structure
PDB1pkj Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii
ChainB
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S118 R122 A131 W133 E145
Catalytic site (residue number reindexed from 1) S118 R122 A131 W133 E145
Enzyme Commision number 3.5.4.30: dCTP deaminase (dUMP-forming).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DUT B H128 I134 D135 F138 T143 E145 H128 I134 D135 F138 T143 E145
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008829 dCTP deaminase activity
GO:0016787 hydrolase activity
GO:0033973 dCTP deaminase (dUMP-forming) activity
Biological Process
GO:0006226 dUMP biosynthetic process
GO:0006229 dUTP biosynthetic process
GO:0009117 nucleotide metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1pkj, PDBe:1pkj, PDBj:1pkj
PDBsum1pkj
PubMed12909016
UniProtQ57872|DCDB_METJA dCTP deaminase, dUMP-forming (Gene Name=dcd)

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