Structure of PDB 1pk8 Chain B

Receptor sequence
>1pk8B (length=292) Species: 10116 (Rattus norvegicus) [Search protein sequence]
ARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFS
VDMEVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVY
NFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKM
GHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKYDVRVQKIG
QNYKAYMRTWKTNTGSAMLEQIAMSDRYKLWVDTCSEIFGGLDICAVEAL
HGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQA
3D structure
PDB1pk8 Tetramerization and ATP binding by a protein comprising the A, B, and C domains of rat synapsin I.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B E373 E386 E248 E261
BS02 ATP B K225 V267 K269 H274 S275 G276 K279 E305 F307 I308 W335 T337 N338 E373 L375 K105 V147 K149 H154 S155 G156 K159 E185 F187 I188 W210 T212 N213 E248 L250 MOAD: Kd=120nM
Gene Ontology
Biological Process
GO:0007269 neurotransmitter secretion
Cellular Component
GO:0008021 synaptic vesicle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1pk8, PDBe:1pk8, PDBj:1pk8
PDBsum1pk8
PubMed14688264
UniProtP09951|SYN1_RAT Synapsin-1 (Gene Name=Syn1)

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