Structure of PDB 1p47 Chain B

Receptor sequence
>1p47B (length=84) Species: 10090 (Mus musculus) [Search protein sequence]
RPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTT
HIRTHTGEKPFACDICGRKFARSDERKRHTKIHL
3D structure
PDB1p47 Constraints for Zinc Finger Linker Design as Inferred from X-ray Crystal Structure of Tandem Zif268-DNA Complexes
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B F116 R118 R124 H125 R142 R146 H149 H153 T156 R170 R174 E177 R180 H181 I184 F14 R16 R22 H23 R40 R44 H47 H51 T54 R68 R72 E75 R78 H79 I82 PDBbind-CN: Kd=2.1fM
BS02 dna B D148 S175 K179 D46 S73 K77 PDBbind-CN: Kd=2.1fM
BS03 ZN B C107 C112 H125 H129 C5 C10 H23 H27
BS04 ZN B C137 C140 H153 H157 C35 C38 H51 H55
BS05 ZN B C165 C168 H181 H185 C63 C66 H79 H83
External links
PDB RCSB:1p47, PDBe:1p47, PDBj:1p47
PDBsum1p47
PubMed12818197
UniProtP08046|EGR1_MOUSE Early growth response protein 1 (Gene Name=Egr1)

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