Structure of PDB 1p16 Chain B

Receptor sequence
>1p16B (length=377) Species: 5476 (Candida albicans) [Search protein sequence]
MVQLEEREIPVIPGNKLDEEETKELRLMVAELLGRRNTGFPGSQPVSFER
RHLEETLMQKDYFVCEKTDGLRCLLFLINDPDKGEGVFLVTRENDYYFIP
NIHFPLSVNETREKPTYHHGTLLDGELVLENRNVSEPVLRYVIFDALAIH
GKCIIDRPLPKRLGYITENVMKPFDNFKKHNPDIVNSPEFPFKVGFKTML
TSYHADDVLSKMDKLFHASDGLIYTCAETPYVFGTDQTLLKWKPAEENTV
DFQLEFVFNEVQYLDYDAKPNLIKLRVWQGSNVHTDFAKLDLSDDDWERL
KALEQPLQGRIAECRQSTTKKGYWEMLRFRNDKSNGNHISVVEKILVSIK
DGVKEKEVIEWCPKISRAWKKRENDRR
3D structure
PDB1p16 Structure of an mRNA capping enzyme bound to the phosphorylated carboxy-terminal domain of RNA polymerase II.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.50: mRNA guanylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y203 H204 Y203 H204
BS02 peptide B R140 R157 P160 L163 G164 Y165 T167 M171 D175 K178 K193 F196 R140 R157 P160 L163 G164 Y165 T167 M171 D175 K178 K193 F196
BS03 GTP B P45 K67 E126 F144 I223 K241 K243 P45 K67 E126 F144 I223 K241 K243
Gene Ontology
Molecular Function
GO:0004484 mRNA guanylyltransferase activity
GO:0005524 ATP binding
Biological Process
GO:0006370 7-methylguanosine mRNA capping
Cellular Component
GO:0031533 mRNA capping enzyme complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1p16, PDBe:1p16, PDBj:1p16
PDBsum1p16
PubMed12820968
UniProtP78587|MCE1_CANAX mRNA-capping enzyme subunit alpha (Gene Name=CGT1)

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