Structure of PDB 1ohs Chain B

Receptor sequence
>1ohsB (length=125) Species: 285 (Comamonas testosteroni) [Search protein sequence]
MNTPEHMTAVVQRFVAALNAGDLDGIVALFADDATVENPVGSEPRSGTAA
IREFYANSLKLPLAVELTQEVRAVANEAAFAFIVSFEYQGRKTVVAPIDH
FRFNGAGKVVSMRALFGEKNIHAGA
3D structure
PDB1ohs Crystal Structure of 5-3-Ketosteroid Isomerase Mutant Y14F/D38N from Pseudomonas Testosteroni Complexed with Androstanedione
ChainB
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F214 N238 A296 D299
Catalytic site (residue number reindexed from 1) F14 N38 A96 D99
Enzyme Commision number 5.3.3.1: steroid Delta-isomerase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 5SD B F214 N238 F254 Y255 F286 D299 F316 F14 N38 F54 Y55 F86 D99 F116
Gene Ontology
Molecular Function
GO:0004769 steroid delta-isomerase activity
GO:0016853 isomerase activity
Biological Process
GO:0008202 steroid metabolic process

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:1ohs, PDBe:1ohs, PDBj:1ohs
PDBsum1ohs
PubMed
UniProtP00947|SDIS_COMTE Steroid Delta-isomerase (Gene Name=ksi)

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