Structure of PDB 1of6 Chain B

Receptor sequence
>1of6B (length=346) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
AEEDVRILGYDPLASPALLQVQIPATPTSLETAKRGRREAIDIITGKDDR
VLVIVGPCSIHDLEAAQEYALRLKKLSDELKGDLSIIMRAYLEKPRVGWK
GLINDPDVNNTFNINKGLQSARQLFVNLTNIGLPIGSEMLDTISPQYLAD
LVSFGAIGARTTESQLHRELASGLSFPVGFKNGTDGTLNVAVDACQAAAH
SHHFMGVTKHGVAAITTTKGNEHCFVILRGGKGTNYDAKSVAEAKAQLPA
GSNGLMIDYSHGNSNKDFRNQPKVNDVVCEQIANGENAITGVMIESNINE
GNQGIPAEGKALKYGVSITDACIGWETTEDVLRKLAAAVRQRREVN
3D structure
PDB1of6 Evolution of Feedback-Inhibited Beta /Alpha Barrel Isoenzymes by Gene Duplication and a Single Mutation.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DTY B E21 D22 E3 D4
BS02 MN B C76 H282 E316 D342 C58 H261 E295 D320
BS03 DTY B T162 Q166 A169 L194 S195 T142 Q146 A149 L174 S175
Gene Ontology
Molecular Function
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity
GO:0016740 transferase activity
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:1of6, PDBe:1of6, PDBj:1of6
PDBsum1of6
PubMed
UniProtP32449|AROG_YEAST Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited (Gene Name=ARO4)

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