Structure of PDB 1o7k Chain B

Receptor sequence
>1o7kB (length=120) Species: 9606 (Homo sapiens) [Search protein sequence]
TFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKT
LKEMFPIEAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCSTLMS
LPTKISRCPHLLDFFKVRPD
3D structure
PDB1o7k Binding of the Px Domain of P47Phox to Phosphatidylinositol 3.4-Bisphosphate and Phosphatidic Acid is Masked by an Intramolecular Interaction
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SO4 B H51 K55 R70 H74 H48 K52 R67 H71
Gene Ontology
Molecular Function
GO:0016176 superoxide-generating NADPH oxidase activator activity
GO:0035091 phosphatidylinositol binding
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function

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Cellular Component
External links
PDB RCSB:1o7k, PDBe:1o7k, PDBj:1o7k
PDBsum1o7k
PubMed12356722
UniProtP14598|NCF1_HUMAN Neutrophil cytosol factor 1 (Gene Name=NCF1)

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