Structure of PDB 1nzl Chain B

Receptor sequence
>1nzlB (length=103) Species: 11889 (Rous sarcoma virus (strain Schmidt-Ruppin)) [Search protein sequence]
AEEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSDFDNA
KGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTNV
CPT
3D structure
PDB1nzl Structural and Thermodynamic Basis for the Interaction of the Src SH2 domain with the Activated form of the PDGF beta-receptor
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B R261 R281 S283 E284 T285 K306 H307 Y308 K309 I320 G342 R11 R31 S33 E34 T35 K56 H57 Y58 K59 I70 G92
External links
PDB RCSB:1nzl, PDBe:1nzl, PDBj:1nzl
PDBsum1nzl
PubMed12706723
UniProtP00524|SRC_RSVSA Tyrosine-protein kinase transforming protein Src (Gene Name=V-SRC)

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