Structure of PDB 1nub Chain B

Receptor sequence
>1nubB (length=226) Species: 9606 (Homo sapiens) [Search protein sequence]
APCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTF
DSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRD
WLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPEKNYNMY
IFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDN
DKYIALDEWAGCFGIKQKDIDKDLVI
3D structure
PDB1nub Crystal structure and mapping by site-directed mutagenesis of the collagen-binding epitope of an activated form of BM-40/SPARC/osteonectin.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B D222 P225 D227 Y229 E234 D162 P165 D167 Y169 E174
BS02 CA B D257 D259 D261 Y263 E268 D197 D199 D201 Y203 E208
BS03 CA B P241 I243 E246 P181 I183 E186
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0005615 extracellular space

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:1nub, PDBe:1nub, PDBj:1nub
PDBsum1nub
PubMed9501084
UniProtP09486|SPRC_HUMAN SPARC (Gene Name=SPARC)

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