Structure of PDB 1nne Chain B

Receptor sequence
>1nneB (length=759) Species: 271 (Thermus aquaticus) [Search protein sequence]
MEGMLKGEGPGPLPPLLQQYVELRDQYPDYLLLFQVGDFYECFGEDAERL
ARALGLVLTHKTSKDFTTPMAGIPLRAFEAYAERLLKMGFRLAVADQVEP
LVRREVTQLLTPGTLLQESLLPREANYLAAIATGDGWGLAFLDVSTGEFK
GTVLKSKSALYDELFRHRPAEVLLAPELLENGAFLDEFRKRFPVMLSEAP
FEPEGEGPLALRRARGALLAYAQRTQGGALSLQPFRFYDPGAFMRLPEAT
LRALEVFEPLRGQDTLFSVLDETRTAPGRRLLQSWLRHPLLDRGPLEARL
DRVEGFVREGALREGVRRLLYRLADLERLATRLELGRASPKDLGALRRSL
QILPELRALLGEEVGLPDLSPLKEELEAALVEDPPLKVSEGGLIREGYDP
DLDALRAAHREGVAYFLELEERERERTGIPTLKVGYNAVFGYYLEVTRPY
YERVPKEYRPVQTLKDRQRYTLPEMKEKEREVYRLEALIRRREEEVFLEV
RERAKRQAEALREAARILAELDVYAALAEVAVRYGYVRPRFGDRLQIRAG
RHPVVERRTEFVPNDLEMAHELVLITGPNMAGKSTFLRQTALIALLAQVG
SFVPAEEAHLPLFDGIYTRIGASDDLAGGKSTFMVEMEEVALILKEATEN
SLVLLDEVGRGTSSLDGVAIATAVAEALHERRAYTLFATHYFELTALGLP
RLKNLHVAAREEAGGLVFYHQVLPGPASKSYGVEVAAMAGLPKEVVARAR
ALLQAMAAR
3D structure
PDB1nne Crystal structure and biochemical analysis of the MutS-ADP-Beryllium Fluoride complex suggests a conserved mechanism for ATP interactions in mismatch repair
ChainB
Resolution3.11 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B K1439 V1445 T1453 P1455 D1472 K433 V439 T447 P449 D466
BS02 dna B P1015 L1016 K1064 N1443 L1470 K1471 R1475 P15 L16 K64 N437 L464 K465 R469
BS03 BEF B S1590 D1662 S584 D656
BS04 ADP B F1567 V1568 N1585 M1586 G1588 K1589 S1590 T1591 H1726 F561 V562 N579 M580 G582 K583 S584 T585 H720
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003690 double-stranded DNA binding
GO:0005524 ATP binding
GO:0030983 mismatched DNA binding
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0006281 DNA repair
GO:0006298 mismatch repair

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1nne, PDBe:1nne, PDBj:1nne
PDBsum1nne
PubMed12582174
UniProtQ56215|MUTS_THEAQ DNA mismatch repair protein MutS (Gene Name=mutS)

[Back to BioLiP]