Structure of PDB 1nlm Chain B

Receptor sequence
>1nlmB (length=350) Species: 562 (Escherichia coli) [Search protein sequence]
KRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGI
EIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGMGGY
VSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNA
EVVGNPVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVA
AKLGDSVTIWHQSGKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWAD
VVVCRSGALTVSEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKIIE
QPQLSVDAVANTLAGWSRETLLTMAERARAASIPDATERVANEVSRVARA
3D structure
PDB1nlm Crystal structure of MurG:UDP-GlcNAc complex reveals common structural principles of a superfamily of glycosyltransferases
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.227: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UD1 B T16 G17 G18 R164 G191 S192 Q193 Q218 F244 I245 M248 G263 L265 T266 E269 T10 G11 G12 R158 G185 S186 Q187 Q212 F238 I239 M242 G257 L259 T260 E263
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
GO:0050511 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity
GO:0051991 UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0030259 lipid glycosylation
GO:0051301 cell division
GO:0071555 cell wall organization
GO:1901137 carbohydrate derivative biosynthetic process
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:1nlm, PDBe:1nlm, PDBj:1nlm
PDBsum1nlm
PubMed12538870
UniProtP17443|MURG_ECOLI UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (Gene Name=murG)

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