Structure of PDB 1nkk Chain B

Receptor sequence
>1nkkB (length=226) Species: 10359 (Human betaherpesvirus 5) [Search protein sequence]
EQQSQAVAPVYVGGFLARYDQSPDEARLLLPRDVVEHWLHAQVALPLNIN
HDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPV
SPLQPDKVVEFLSGSYAGLSLSSRRCDETTPFKHVALCSVGRRRGTLAVY
GRDPEWVTQRFPDLTAADRDGLRAQWQRCGGDPFRSDSYGLLGNSVDALY
IRERLPKLRYDKQLVGVTERESYVKA
3D structure
PDB1nkk Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease
ChainB
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H363 S432 S434 H457 R465 R466
Catalytic site (residue number reindexed from 1) H51 S120 S122 H134 R142 R143
Enzyme Commision number 3.4.21.97: assemblin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R331 H363 S432 L433 S434 S435 R436 R437 G464 R465 R27 H51 S120 L121 S122 S123 R124 R125 G141 R142
BS02 peptide B H363 S432 H51 S120
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1nkk, PDBe:1nkk, PDBj:1nkk
PDBsum1nkk
PubMed12549906
UniProtP16753|SCAF_HCMVA Capsid scaffolding protein (Gene Name=UL80)

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